Visual Analytics for Protein Feature Discovery

Scott Barlowe
April 7, 2011 - 12:30 PM
Woodward 130
The knowledge gained from biology datasets can streamline and speed-up pharmaceutical development. However, computational models generate so much information regarding protein behavior that large-scale analysis by traditional methods is almost impossible. The volume of data produced makes the transition from data to knowledge difficult and hinders biomedical advances. Over two years of collaboration with protein scientists has resulted in a novel visual analytics approach named WaveMap for exploring data generated by a protein flexibility model. WaveMap integrates wavelet analysis, visualizations, and interactions to facilitate the browsing, feature identification, and comparison of protein attributes represented by two-dimensional plots. A fully working prototype of WaveMap is complete and its effectiveness is illustrated by a user scenario. The talk will conclude by explaining current work in subspace exploration and possible future directions.